![]() Clinical features include lymphadenopathy and hepatosplenomegaly, but some individuals present with extranodal involvement and abnormal lab findings. Like Hodgkin lymphoma, which has distinct pathologic features and treatments, NHL often presents with constitutional signs of fever, night sweats, and weight loss. Most pediatric cases are aggressive and high-grade (but curable) in adults, low-grade subtypes are more common. Non-Hodgkin lymphomas (NHLs) are a diverse group of hematologic malignancies that are clonal proliferative disorders of mature or progenitor B cells, T cells, or natural killer (NK) cells. Madison (WI): University of Wisconsin Hospitals and Clinics Authority c2022. Health Information: Health Facts for You: 24-Hour Urine Collection. Philadelphia: Trustees of the University of Pennsylvania c2022. Department of Health and Human Services Tumor Markers. Tests for Brain, Spinal Cord, and Nerve Disorders. Test ID: B2MU: Beta-2 Microglobulin (B2M), Urine: Clinical and Interpretive. Mayo Foundation for Medical Education and Research c1995–2022.
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